Codex Gamicus

In 2001, the Nintendo GameCube and the Xbox, two new systems, were featured. They would both be released later in the year.

Microsoft held its press conference unveiling their first season of games for the Xbox. Some notable mentions include: Oddworld: Munch's Oddysee, Enclave, Jet Set Radio Future, Amped: Freestyle Snowboarding, Mad Dash, Project Gotham Racing, Project Ego, Medal of Honor: Allied Assault, Dead or Alive 3, Gunvalkyrie and Halo: Combat Evolved.

Nintendo also made its first American unveiling of the GameCube in this event. Some notable games included Luigi's Mansion, Pikmin, Wave Race: Blue Storm, Super Smash Bros. Melee, Cel Damage, Eternal Darkness: Sanity's Requiem, Super Monkey Ball, and Star Fox Adventures. Nintendo's Game Boy Advance, unveiled at an earlier Spaceworld was almost absent from E3 2001.

This year was also the last E3 appearance of the Dreamcast. Some games included Sonic Adventure 2, Ooga Booga, and Bomberman Online. It was held in Los Angeles. The expo received 62,000 attendees, a 37.78% increase over the previous year's event.