In Animal Shelter, most of the time, the cats in the game require more brushing than dogs do. For the dogs, the brush is just something that makes them happy, while brushing cats is associated with their health and hygiene as well. However, dogs do get dirtier than cats and they will need a washing and a good scrub from time to time in the washing station where they can use water shampoo and a hairdryer to clean them.
Animal health also depends on how clean their cages are, so the player needs to make sure the cages are clean.
Some pets will be injured at some point, hence why the player will need medical supplies that they can find in the shop such as (bandages, pills, syringes, bandaids, etc.). By taking the blood sample and sending it to a vet, the player will get a mail on how to further take care of the sick animal. When they heal the injured animal, the player can put it back in the fence to recover and get ready for adoption.